Fig. 1: Miami plots of sex-specific associations. | Nature Communications

Fig. 1: Miami plots of sex-specific associations.

From: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

Fig. 1: Miami plots of sex-specific associations.

a FI sex-specific associations, b FG sex-specific associations showing women on upper panel (all y axis values are positive) and men on lower panel (all x axis values are negative). Established or novel loci with sex-dimorphic effects (Psex-dimorphic ≤ 5.0 × 10−8) and nominal sex heterogeneity (Pheterogeneity < 0.05) are shown in magenta (larger effect in women) or cyan (larger effect in men). Novel genome-wide significant loci from sex-combined analyses with sex-homogeneous effects (Psex-combined ≤ 5.0 × 10−8) are shown in yellow. Established loci reaching genome-wide significance in sex-combined analyses and showing no sex heterogeneity (Pheterogeneity > 0.05) are colored in purple. All remaining established loci (i.e. no significant sex-dimorphic or sex-homogeneous effects) are marked in orange.

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