Fig. 4: Structures with the linker region.
From: Structural insights into the mechanism of rhodopsin phosphodiesterase
a Overall structure of Rh-PDE TMD–Linker. The linker region is colored gray. b Overall structure of Rh-PDE Linker–PDE. The newly observed region, as compared to the previous structure (PDB ID: 5VYD), is shown as gray bold coils. Zinc and magnesium ions are colored gray and green, respectively. c Glu478 and the backbone of the newly observed region are shown as stick models. Dashed lines show hydrogen bonds. d Ribbon diagrams of the linker structure of Rh-PDE TMD–Linker. e Ribbon diagrams of the linker region structure, modeled with Rosetta. f Ribbon diagrams of the final structure from the aMDdual simulation.
