Fig. 3: Monostable GRN and co-expressional localization at the low-density limit. | Nature Communications

Fig. 3: Monostable GRN and co-expressional localization at the low-density limit.

From: From deterministic to fuzzy decision-making in artificial cells

Fig. 3

a Production rate of CIts-mVenus proteins in 15 s inside individual compartments (left column) and ensemble production rates (right column) as in Fig. 2c. Circle with error bars give the median and the 32th to 68th percentile of the ensemble production rates (N = 1044, 1392, 1044, 1044, 1044 in the order of increasing temperature). b Illustration of the expected PRM activity with temperature in the monostable GRN and the corresponding states. c A protein repressor synthesized in proximity to its DNA-binding site, reach higher effective concentrations by co-expression localization (left scheme) than in an equilibrium scenario due to diffusion away from the DNA (right scheme). d Ensemble production rates obtained from stochastic simulations with a scan in the CIts binding rate to the DNA-binding sites. Source data are provided as a Source data file.

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