Fig. 2: Associations of lipid class totals with prevalent and incident Alzheimer’s disease. | Nature Communications

Fig. 2: Associations of lipid class totals with prevalent and incident Alzheimer’s disease.

From: Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer’s disease

Fig. 2: Associations of lipid class totals with prevalent and incident Alzheimer’s disease.

Forest plots of lipid class associations for a prevalent Alzheimer’s disease (logistic regression, AIBL = 268 cases, 696 control, ADNI = 178 cases, 210 controls) and b incident Alzheimer’s disease (Cox regression, AIBL = 68 cases, 714 controls, ADNI = 166 cases, 397 controls). Lipid classes are generated by the sum of each individual species measured in each class. Regressions are adjusted for age, sex, BMI, total cholesterol, HDL-C, triglycerides, number of APOE4 alleles, statin use and omega-3 supplementation. AIBL was further adjusted for time points (only in logistic regression analysis) and site of blood collection. ADNI was further adjusted for fasting status.

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