Fig. 3: Associations of individual lipid species with prevalent Alzheimer’s disease.
From: Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer’s disease
Forest plot outlining the logistic regression results of individual species, between controls and prevalent AD in both the AIBL (blue n = 268 cases, 696 controls) and ADNI (red, n = 178 cases, 210 controls) cohorts with the combined meta-analysis in the middle (green). P value was corrected for multiple comparison using approach by Benjamini and Hochberg. Covariates include age, sex, BMI, total cholesterol, HDL-C, triglycerides, number of APOE4 alleles, statin use and omega-3 supplementation. Additional covariates for AIBL include site of blood collection and time point while ADNI includes fasting status. Open circles, not significant; closed dark circles, significant after FDR correction; coloured circles, top 20 associations ranked by p value.
