Table 1 Summary of sequencing statistics.
From: PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia
Subset | N Variants | Unweighted p value | Odds ratio | 95% Confidence interval |
|---|---|---|---|---|
Discovery cohort | ||||
All PCM1 variants | 293 | 0.068 | 1.149 | 1.115–1.184 |
MAF < 5% | 248 | 0.033 | 1.358 | 1.247–1.487 |
MAF < 1% | 202 | 0.012 | 1.373 | 1.140–1.664 |
MAF < 0.1% | 125 | 0.002 | 1.642 | 1.158–2.386 |
All non-synonymous variants | 21 | 0.02 | 3.007 | 1.213–8.708 |
Replication cohort | ||||
All PCM1 variants | 278 | 0.115 | 1.048 | 1.002–1.097 |
All non-synonymous variants | 17 | 0.006 | 4.179 | 1.213–8.708 |
