Fig. 5: COPD-associated species correlate with metabolites differentiating COPD (nā=ā28) and healthy (nā=ā29) individuals.

Species and metabolites included are those identified as significantly differential between COPD and healthy samples, including age, sex and BMI within the relevant models (Supplementary DataĀ 7 and 21). Enrichment in either group indicated by coloured bars to the left and top of the plot. Significant correlations denoted by white stars (*pā<ā0.05; **pā<ā0.01, Studentās t test (two-sided), BenjaminiāHochberg adjustment for multiple comparisons. Exact p values are provided in Supplementary DataĀ 35). Higher taxonomy of species (order, family) and super pathway of metabolites are indicated by coloured bars.