Fig. 2: Kinetic assessment of the antigen-specific humoral responses.
From: Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report
Serological reactivity to SARS-CoV-2 spike a and nucleocapsid b antigens of patient sera obtained at indicated time points, the first (CP 1) and second (CP 2) infusions of convalescent plasma (CP), sera from healthy controls (n = 8 biologically independent subjects) and patients (n = 5 biologically independent subjects) with PCR-confirmed COVID-19 (MFI, mean fluorescence intensity; Mean and SEM). c Neutralisation activity against SARS-CoV-2 spike-pseudotyped lentiviral particles of patient sera obtained at indicated time points, compared with the first (CP 1) and second (CP 2) infusions of convalescent plasma (CP). (n = 1 independent biological samples, n = 3 technical replicates from each sample; mean and SD). Data from one independent experiment.
