Fig. 2: Intratumoral DCs and NK cells correlate with CD3E gene expression in human neuroblastoma. | Nature Communications

Fig. 2: Intratumoral DCs and NK cells correlate with CD3E gene expression in human neuroblastoma.

From: Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma

Fig. 2: Intratumoral DCs and NK cells correlate with CD3E gene expression in human neuroblastoma.

Box plots of metagene expression values for the indicated immune cell types28 according to the high (Hi) and low (Lo) levels of CD3E mRNA (median split) in primary NB patients from Nanostring-NB (n = 36) and the SEQC-NB (n = 498) cohorts. The immune cell type scores were calculated as the average expression values of the NanoString constituent genes. The boxes show the 25th to 75th percentile; the horizontal lines inside the box represent the median; the upper whisker extends to the largest data point, no more than 1.5 times the IQR from the box; the lower whisker extends to the smallest data point at most 1.5 times the IQR from the box; the dots are individual samples. Data were analyzed by Kruskal–Wallis rank-sum test (two-sided). No adjustment was required. Statistically significant P values are indicated.

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