Fig. 1: Scatter and leave one out plots demonstrating influential outliers in univariable MR of alcohol consumption and oral and oropharyngeal cancer risk. | Nature Communications

Fig. 1: Scatter and leave one out plots demonstrating influential outliers in univariable MR of alcohol consumption and oral and oropharyngeal cancer risk.

From: A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer

Fig. 1: Scatter and leave one out plots demonstrating influential outliers in univariable MR of alcohol consumption and oral and oropharyngeal cancer risk.The alt text for this image may have been generated using AI.

a Scatter plot showing ADH1B (rs1229984), an outlier single nucleotide polymorphism in the analysis of alcohol consumption (drinks per week, n = 941,280) and oral and oropharyngeal cancer risk (n = 6034 cases and 6585 controls). b Leave one out plot again demonstrating the ADH1B (rs1229984) influential outlier. Consistent evidence for a causal effect of alcohol on oral and oropharyngeal cancer risk was found even when this variant was excluded from the analysis. Effect estimates are reported per SD increase in the exposure and error bars represent 95% confidence intervals.

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