Fig. 2: In the presence of subinhibitory concentration of cefoxitin, diverse antibiotic classes and non-antibacterial therapeutic drugs select in favour of mecA. | Nature Communications

Fig. 2: In the presence of subinhibitory concentration of cefoxitin, diverse antibiotic classes and non-antibacterial therapeutic drugs select in favour of mecA.

From: Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments

Fig. 2

Of all tested compounds, 15% (8421/58,038 compounds analysed in Single-Dose and Dose-Response assays and compounds analysed only in Dose-Response assay, Methods) showed selection activity in favour of mecA, of which 4% (332) were compounds of known anatomical therapeutic chemical (ATC) drug groups as indicated (legend for abbreviations: B blood and blood forming organs; V various; H systemic hormonal preparations, excluding sex hormones and insulins; J antiinfectives for systemic use; J01 antibacterials for systemic use; J02 antimycotics for systemic use; J04 antimycobacterials; J05 antivirals for systemic use; J06 immune sera and immunoglobulins). Drugs belonging to more than one ATC drug group were counted once for each group. Source data are provided as a Source Data file.

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