Fig. 4: Per-slide AUC values for cross-classification of tumor/normal status.

The hierarchically clustered heatmap shows pairwise AUC values of CNNs trained on the tumor/normal status of one cancer type (train axis) tested on the tumor/normal status of another cancer type (test axis). Adeno-ness (adenocarcinoma vs. non-adenocarcinoma) and organ of origin (lung, kidney, gastrointestinal, gynecological) for each set are marked with colors on the margins. Cancers with ambiguous or mixed phenotype are marked as “Other”.