Fig. 3: Mutational landscape revealed by ctDNA profiling.
From: Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients
a Heatmap illustrating the top 20 most common mutant genes. Color gradation represents the mutational prevalence of each gene in different cancer types. The right bars indicate the distribution of different mutational types for each displayed gene. b Mutational prevalence of driver genes in our ctDNA and MSKCC cohorts. Putative driver genes in different cancer types are displayed. Symbol colors correspond to different cancer types. The statistical test used is two-tailed Pearson correlation test. GIST gastrointestinal stromal tumor, HCC hepatocellular carcinoma, NSCLC non-small cell lung cancer, SCLC small cell lung cancer, UGI upper gastrointestinal cancer.
