Fig. 2: Overall structure of the hnRNPA1 LC fibril. | Nature Communications

Fig. 2: Overall structure of the hnRNPA1 LC fibril.

From: The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure

Fig. 2

a The primary sequence of the hnRNPA1 fibril core. Residues forming the β-strand are highlighted in red. Glycine residues are in blue. Secondary structures are indicated below. b Top view of the cryoEM structure of hnRNPA1 LC fibril. Six layers of backbones are shown. The structure is colored by chain. The pseudo-2-fold screw axis is indicated. The sheet kink region is zoomed in with side chains shown. c Side views of the fibril structure in b.

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