Fig. 6: Shifting promoters.
From: TBPL2/TFIIA complex establishes the maternal transcriptome through oocyte-specific promoter usage
a, b Analysis of the TBPL2-dependent versus TBPL2-independent shifting promoters within a −250/+250 region centred on the position of the TBPL2-independent transcription start sites (TSS) clusters (position + 1 in (a, b) and red dashed line in (b)). Position of the TBPL2-dependent (blue) and of the TBPL2-independent (orange) dominant TSSs for each shifting promoter sequence (a) and WW dinucleotide enrichment heatmap (l) from the same set of sequences ordered as in (b). c Distribution of the best TATA box PWM matches within a −35 to −20 region upstream of the TBPL2-dependent (blue) and TBPL2-independent (orange) dominant TSS of the shifting promoters. The dashed lines indicate the median of the TATA box PWM matches for the TBPL2-dependent (blue) and the TBPL2-independent (orange) shifting TSS clusters (P value after a two-tailed Wilcoxon rank-sum test).
