Fig. 1: The preparation and mechanism of H@Gd-NCPs. | Nature Communications

Fig. 1: The preparation and mechanism of H@Gd-NCPs.

From: Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress

Fig. 1

a Schematic illustration of the preparation of nanoscale coordination polymers H@Gd-NCPs. b The mechanism of H@Gd-NCPs for radiosensitization via amplifying intracellular oxidative stress to potentiate checkpoint blockade immunotherapies. Dendritic cells (DCs), glutathione (GSH), oxidized glutathione (GSSG), hydroxyl radicals (•OH), calreticulin (CRT), high mobility group protein B1 (HMGB1), adenosine triphosphate (ATP).

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