Fig. 3: Enzyme-mimetic properties and ROS scavenging activity of Au25 clusterzymes. | Nature Communications

Fig. 3: Enzyme-mimetic properties and ROS scavenging activity of Au25 clusterzymes.

From: Catalytically potent and selective clusterzymes for modulation of neuroinflammation through single-atom substitutions

Fig. 3: Enzyme-mimetic properties and ROS scavenging activity of Au25 clusterzymes.The alternative text for this image may have been generated using AI.

a The radar map of enzymatic activities and free radical scavenging abilities of various clusterzymes. b Schematic illustration of catalytic selectivity of the clusterzyme system. Au25 exhibits significant superiority in GPx-like activity; Au24Cu1 shows advantages in the CAT-like activity through the Cu single active site; Au24Cd1 preferably exhibits the SOD-like activity via the Cd single active site, each demonstrating a unique catalytic selectivity. c GPx-, d CAT-, and e SOD-like activities of Au25, Au24Cu1, and Au24Cd1. ROS scavenging activities of Au25, Au24Cu1, and Au24Cd1 clusterzymes for f •OH and g O2•− studied by the ESR spectroscopy. BMPO is used as the ROS-capturing agent and the sources of •OH and O2•− are H2O2 and KO2, respectively. h Corresponding quantifications of the scavenging efficiencies (n = 3 independent experiments, data are presented as mean ± SD).

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