Fig. 3: The bis-silylation reaction of TMDQ reagent 1 with terminal alkyne 2. | Nature Communications

Fig. 3: The bis-silylation reaction of TMDQ reagent 1 with terminal alkyne 2.

From: Bis-silylation of internal alkynes enabled by Ni(0) catalysis

Fig. 3: The bis-silylation reaction of TMDQ reagent 1 with terminal alkyne 2.

Standard reaction conditions: disilane 1a (52 mg, 0.2 mmol), terminal alkyne 2 (41 mg, 44 μL, 0.4 mmol), Pd(acac)2 (3 mg, 0.01 mmol), t-OcNC (17 mg, 0.12 mmol), and t-BuOK (2.3 mg, 0.02 mmol) in toluene (2 mL) at 120 °C under N2 atmosphere for 24 h. See Supplementary Information (SI) for details.

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