Fig. 3: Thiol/disulfide catalyzed DCC.
From: Biomimetic selenocystine based dynamic combinatorial chemistry for thiol-disulfide exchange
a DCC general scheme. b Building blocks of DCL. c Sulfur and selenium Cys and Sec derivatives. The pKa corresponds to the thiol group. Estimated pKas data calculated with Epik as implemented in Schrödinger Suite Release 2020-254,55,56 and reported in the literature (Sec pKa29, Cys pKa30). See Supplementary Fig. 1 for pKa calculations.
