Table 2 Univariate and multivariate Fine-Gray regression in the training cohort.

From: Predicting postoperative peritoneal metastasis in gastric cancer with serosal invasion using a collagen nomogram

Variable

Univariate analysis

Multivariate analysis

SHR (95% CI)

P value

SHR (95% CI)

P value

Collagen signature

4.11 (2.58–6.56)

<0.001

2.49 (1.52–4.08)

<0.001

Age

0.99 (0.98–1.02)

0.62

Ā Ā 

Sex (Female vs. Male)

0.87 (0.53–1.43)

0.58

Ā Ā 

BMI (≄24 kg/m2 vs. <24 kg/m2)

1.14 (0.69–1.89)

0.61

Ā Ā 

CEA (Elevated vs. Normal)

1.08 (0.67–1.73)

0.76

Ā Ā 

CA 19-9 (Elevated vs. Normal)

1.58 (0.98–2.55)

0.064

Ā Ā 

Tumour location

Ā 

0.56

Ā Ā 

Ā Ā Ā Antrum of the stomach

Reference

>0.99

Ā Ā 

Ā Ā Ā Body of the stomach

1.32 (0.80–2.19)

0.28

Ā Ā 

Ā Ā Ā Cardia of the stomach

1.07 (0.60–1.90)

0.82

Ā Ā 

Tumour size (≄4 cm vs. <4 cm)

3.32 (1.99–5.52)

<0.001

2.35 (1.37–4.02)

0.002

Lauren classification (Diffuse or mixed vs. Intestinal)

1.30 (0.82–2.07)

0.27

Ā Ā 

Differentiation status

Ā 

0.001

Ā 

0.12

Ā Ā Ā Well + Moderate

Reference

>0.99

Reference

>0.99

Ā Ā Ā Poor

2.35 (1.18–4.69)

0.015

1.42 (0.66–3.05)

0.37

Ā Ā Ā Undifferentiated

3.67 (1.81–7.47)

<0.001

2.12 (0.96–4.72)

0.065

Lymph node metastasis

Ā 

<0.001

Ā 

0.060

Ā Ā Ā N0

Reference

>0.99

Reference

>0.99

Ā Ā Ā N1

3.16 (1.35–7.44)

0.008

2.47 (1.02–6.20)

0.044

Ā Ā Ā N2

3.32 (1.33–8.24)

0.01

2.50 (1.01–6.20)

0.047

Ā Ā Ā N3a

6.18 (2.67–14.29)

<0.001

3.22 (1.25–8.31)

0.016

Ā Ā Ā N3b

9.28 (3.94–21.87)

<0.001

4.43 (1.65–11.94)

0.003

Chemotherapy (Yes vs. No)

0.75 (0.46–1.23)

0.26

Ā Ā 
  1. Association of all variables with peritoneal metastasis is analyzed using a two-sided Gray’s test.
  2. BMI body mass index, CA carbohydrate antigen, CEA carcinoembryonic antigen, CI confidence interval, SHR subdistribution hazard ratio.