Fig. 1: Bendiocarb is detectable at high levels in maternal plasma, is trans-placentally transferred to the fetus, and is present in infants at 8 weeks of life. | Nature Communications

Fig. 1: Bendiocarb is detectable at high levels in maternal plasma, is trans-placentally transferred to the fetus, and is present in infants at 8 weeks of life.

From: Exposure to pesticides in utero impacts the fetal immune system and response to vaccination in infancy

Fig. 1: Bendiocarb is detectable at high levels in maternal plasma, is trans-placentally transferred to the fetus, and is present in infants at 8 weeks of life.

a Timing of household bendiocarb spraying by gestational week. b Maternal plasma bendiocarb concentration at the time of delivery, by gestational week of exposure (n = 167, Spearman’s correlation). The dotted line indicates an LLOQ of 10 pg/mL. c Bendiocarb concentration was evaluated in available plasma from unexposed and exposed maternal plasma at delivery, exposed cord plasma, exposed infant plasma at 8 weeks of life (prior to repeat household pesticide exposure, LLOQ 10 pg/mL, Wilcoxon signed-rank test, single replicate). Bendiocarb was detected above the lower limit of quantification in 0/12 (0%) of unexposed maternal plasma at delivery, 143/167 (86%) of exposed maternal plasma at delivery, 51/109 (47%) of exposed cord plasma, and 66/114 (58%) of exposed infant plasma at 8 weeks of life. Two-sided p values were calculated for all test statistics.

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