Table 1 Ubiquitination clusters with potential regulatory circadian functions.
Gene name | UniprotID | Proximity score (p-value) | Cycling ubiquitination sites | Membrane (GOCC) | Region/domain |
|---|---|---|---|---|---|
SLC7A5 (LAT1) | Q01650 | 0.0015 | K19, K25, K30 | x | N-terminus |
SLC16A1 (MCT1) | P53985 | 0.0036 | K216, K223, K224 | x | Cytosolic loop |
LAYN | Q6UX15 | 0.0064 | K272, K273, K297, K311 | ||
EPB41L5 | Q9HCM4 | 0.0073 | K508, K510 | x | |
MYH9 | P35579 | 0.0079 | K555, K651, K760, K821 | x | Myosin motor, interaction with LIMCH1 |
RTN4 (NOGO) | F8W914 | 0.0094 | K327, K332, K336 | x | Reticulon, C-terminus |
ABHD17B | Q5VST6 | 0.0098 | K206, K207 | x | |
SLC3A2 (MDU1) | F5GZS6 | 0.0153 | K114, K116 | x | |
SLC7A11 (xCT) | Q9UPY5 | 0.0161 | K4, K30, K37 | x | N-terminus |
PCNP | Q8WW12 | 0.0182 | K94, K96 | ||
SCRIB (LAP4) | A0A0G2JNZ2 | 0.0184 | K53, K63 | x | N-terminus |
PLXNB2 | O15031 | 0.0189 | K1743, K1757 | C-terminus | |
TOM1 | O60784-2 | 0.0209 | K443, K446 | x | C-terminus |
VLDLR | P98155 | 0.0220 | K828, K839 | x | C-terminus |
H2AFY | O75367 | 0.0240 | K292, K295 | Macro | |
SLC20A1 (GLVR1, PIT1) | Q8WUM9 | 0.0262 | K286, K320, K394, K399, K456 | x | Cytosolic loop |
KSR1 | A0A0A0MQW1 | 0.0284 | K92, K101 | x | |
HAS2 | Q92819 | 0.0311 | K73, K80 | ||
SMARCD2 | B9EGA3 | 0.0318 | K200, K207 | ||
TAX1BP1 (T6BP) | Q86VP1-2 | 0.0321 | K561, K571 | ||
SLC20A2 (GLVR2, PIT2) | Q08357 | 0.0394 | K262, K272 | x | Cytosolic loop |
HSP90AB1 (HSP90B) | P08238 | 0.0411 | K568, K577 | x | Interaction with NR3C1 |
SLC12A2 (NKCC1) | G3XAL9 | 0.0420 | K237, K948, K958, K966, K971, K976, K983, K991, K992, K1125 | x | SLC12 |
PCDHB5 | Q9Y5E4 | 0.0426 | K767, K784 | x | C-terminus |
PPAP2B (LPP3) | O14495 | 0.0455 | K8, K15 | x | N-terminus |
SCAMP1 | A0A087WXB0 | 0.0465 | K63, K71 | x | N-terminus |
