Fig. 3: Dwarfism of Mll4-cKO mice. | Nature Communications

Fig. 3: Dwarfism of Mll4-cKO mice.

From: The histone H3-lysine 4-methyltransferase Mll4 regulates the development of growth hormone-releasing hormone-producing neurons in the mouse hypothalamus

Fig. 3

a Mll4-cKO mice are smaller than their littermate control mice (a representative image for males). b–e A significant reduction in body weight (b), linear length (c), liver Igf1 mRNA levels (d), and serum glucose levels (e) in male and female Mll4-cKO mice relative to their littermate control mice at P40. The number of mice used is as indicated below each genotype in parenthesis (b–e). Statistical differences were determined by two-sided Student’s t-test; *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001. Column bars represent mean, error bars indicate the SD (b–e).

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