Fig. 2: H2A.B is expressed in a broad array of cancers.

a Heat map illustrating the co-expression of H2A.B paralogues in individual tumors that express any one H2A.B paralogue (at >1.5 TPM as measured by RNA-seq), for cancer types with at least 10 tumors expressing any H2A.B paralogue. Percentages of tumors for each cancer type that express any H2A.B paralogue are shown. b Expression levels (TPM) of H2A.B-encoding transcripts in three independent B-acute lymphoblastic leukemia data sets, horizontal line demarcates 1.5 TPM as measured by RNA-seq. Only samples with non-zero expression of any H2A.B paralog are shown: 18, 5, and 1 samples are omitted from Liu et al. 2016, Qian et al. 2017, and Yasuda et al. 2016, respectively. c As in b, but for cancer cell lines from CCLE, grouped by their lineage. Only lineages with any sample >1.5 TPM, and samples with non-zero expression of any H2A.B paralog are shown.