Fig. 4: Venn diagram of the involvement of identified genes in inborn errors of metabolism (IEMs). | Nature Communications

Fig. 4: Venn diagram of the involvement of identified genes in inborn errors of metabolism (IEMs).

From: Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism

Fig. 4: Venn diagram of the involvement of identified genes in inborn errors of metabolism (IEMs).

All of the known IEMs are recessively inherited. Genes for which no IEMs are yet identified represent candidate genes in individuals with extreme levels of the implicated metabolites. Gray font is used for OR5R1 because of the extended linkage disequilibrium in the region extending to FOLH1, which may therefore not represent an independent signal.

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