Fig. 3: 3I14 Somatic hypermutations shape HCDR3. | Nature Communications

Fig. 3: 3I14 Somatic hypermutations shape HCDR3.

From: Unique structural solution from a VH3-30 antibody targeting the hemagglutinin stem of influenza A viruses

Fig. 3: 3I14 Somatic hypermutations shape HCDR3.

a Sequences for 3I14 heavy- and light-chain wild type and germline. Somatic hypermutations (SHMs) are in bold. b SHMs on the 3I14 heavy and light chains are shown as white sticks and labeled. c Zoomed in box from b showing the SHMs that surround the HCDR3 as white transparent surfaces and sticks. HCDR3 is shown as a cartoon and sticks. The HCDR3 is shaped by interactions with the SHMs, which surround it.

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