Fig. 1: TEM images of soft and hard BCs on the surface of NPs. | Nature Communications

Fig. 1: TEM images of soft and hard BCs on the surface of NPs.

From: Nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation

Fig. 1

Clusters of biomolecules are visible on both the carbon support film of the Cu TEM grid and the surface of the NPs before washing (a, b), and in the hard corona of NPs after washing three times (c, d). Higher-magnification images (b, d) of the surface of a single NP shows the clusters of biomolecules in the hard corona. Note the absence of larger clusters in the background of the unwashed sample.

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