Fig. 2: Cryo-EM images of the PS-COOH NPs obtained with a direct electron detector and phase plate. | Nature Communications

Fig. 2: Cryo-EM images of the PS-COOH NPs obtained with a direct electron detector and phase plate.

From: Nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation

Fig. 2

a Original NPs without corona; b NPs with corona; c, d higher magnification of the NPs showing the distribution of biomolecules and their association with the surface of the NPs. Nonspecific proteins accumulate between the NPs as large clusters (black arrows). The black dots in the images are 10 nm gold fiducial markers.

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