Fig. 2: The antiviral activity of GRL-1720 and compound 5h against SARS-CoV-2.
VeroE6 cells were exposed to SARS-CoVWK-521 for 1 h, the virus was washed out, and the virus-exposed VeroE6 cells were cultured for 3 days. The viral copy numbers in the culture supernatants were determined using RT-qPCR. Red and black lines indicate reduction of viral copy numbers and cytotoxicity, respectively. Each compound was tested upon at least three different occasions. The data in Fig. 2 are representative ones. Both graphs were generated with Microsoft Excel. EC50 values shown denote means ± 1 S.D. All compounds shown in Fig. 2 were tested and compared in one assay performed in duplicate (n = 2). Source data are provided as a Source Data file.
