Table 5 Association of PHS with aggressive prostate cancer, by two clusters using fastSTRUCTURE.

From: Polygenic hazard score is associated with prostate cancer in multi-ethnic populations

fastSTRUCTURE K

Cluster

HR80/20: ≥80th vs. ≤20th

K = 2

1

5.60 [5.55–5.64]

2

2.06 [2.03–2.09]

Admixed

5.05 [4.89–5.21]

  1. Hazard ratios (HRs) from Cox proportional hazards models are shown comparing men in the highest 20% of genetic risk (≥80th percentile) vs. the lowest 20% of genetic risk (≤20th percentile).
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