Fig. 2: SARS-CoV-2 titer heterogeneity over time.

A The line graph shows the trajectory of the humoral immune response after the first antibody-positive timepoint (red lines show individuals that experience an increase in their antibody titers and gray shows individuals that exhibit stable or low-level waning) (n = 48). B The violin plots show the T0 and T1 RBD-specific IgG titers across individuals that experience an increase (reds) or experience stable or decreasing (grays). C The line plot shows the overall decay profiles once all samples were aligned based on study maximum observed titer (highest titer per individual observed in this study) (n = 32). The shades of blue show the individuals with the higher study maximum titers in the deep blue or lower observed titers in the light blue. Statistical differences between T0 and T1 within a group in (A) and (B) were assessed with a paired Wilcoxon-test and differences across groups and timepoints were assessed with the Kruskal–Wallis test followed by a post hoc Dunn’s correction for multiple testing. ****p < 0.0001 or exact p-values for not significant comparisons. Source data are provided as a Source Data file.