Table 1 Phosphosites that were enriched following Pf-derived EV treatment.
From: 20S proteasomes secreted by the malaria parasite promote its growth
Phosphosite | No. of identifications | |||||||
|---|---|---|---|---|---|---|---|---|
Protein | Protein name | Position | Gene names | Pf 5 min | Pf 15 min | uRBC 5 min | uRBC 15 min | Amino acid |
P35611 | α-adducin | 364 | ADD1 | 3 | 5 | 1 | 1 | T |
P35612 | β-adducin | 699 | ADD2 | 4 | 2 | 0 | 2 | S |
Q9UEY8 | γ-adducin | 679 | ADD3 | 3 | 1 | 0 | 0 | S |
P16157 | Ankyrin-1 | 1075 | ANK1 | 3 | 2 | 0 | 1 | T |
P16157 | Ankyrin-1 | 960 | ANK1 | 6 | 6 | 3 | 3 | S |
P16157 | Ankyrin-1 | 1696 | ANK1 | 5 | 6 | 2 | 3 | S |
P16157 | Ankyrin-1 | 1646 | ANK1 | 1 | 2 | 0 | 0 | S |
H7BZV9 | Ankyrin repeat domain 54 | 76 | ANKRD54 | 3 | 1 | 0 | 1 | S |
K7N7A8, P29972 | Aquaporin-1 | 426 | AQP1 | 0 | 3 | 0 | 0 | T |
P23634 | ATPase plasma membrane Ca2+ | 1162 | ATP2B4 | 0 | 4 | 0 | 0 | S |
O14523 | C2CD2 like | 470 | C2CD2L | 3 | 2 | 0 | 1 | S |
O14523 | C2CD2 like | 613 | C2CD2L | 1 | 2 | 0 | 0 | S |
P00918 | carbonic anhydrase 2 | 165 | CA2 | 3 | 1 | 0 | 2 | S |
E7EQ12 | Calpastatin | 81 | CAST | 1 | 2 | 0 | 0 | S |
E9PS23 | Cofilin 1 | 24 | CFL1 | 1 | 2 | 0 | 0 | S |
Q08495 | Dematin | 285 | DMTN | 1 | 3 | 0 | 0 | S |
Q08495 | Dematin | 124 | DMTN | 1 | 3 | 0 | 0 | S |
Q08495 | Dematin | 333 | DMTN | 4 | 5 | 3 | 0 | S |
Q7L9B9 | Endonuclease/exonuclease/ phosphatase family domain containing 1 | 173 | EEPD1 | 3 | 4 | 0 | 2 | S |
Q8N3D4 | EH domain binding protein 1 like 1 | 191 | EHBP1L1 | 2 | 1 | 0 | 0 | S |
E7EX73 | Eukaryotic translation initiation factor 4 gamma 1 | 1046 | EIF4G1 | 2 | 1 | 0 | 0 | S |
P11171 | Erythrocyte membrane protein band 4.1 | 200 | EPB41 | 1 | 2 | 0 | 0 | S |
Q5T0W9 | Family with sequence similarity 83 member B | 766 | FAM83B | 5 | 4 | 0 | 2 | S |
Q0JRZ9 | FCH domain only 2 | 488 | FCHO2 | 3 | 3 | 0 | 1 | S |
Q0JRZ9 | FCH domain only 2 | 496 | FCHO2 | 1 | 2 | 0 | 0 | S |
Q86UX7 | Fermitin family member 3 | 347 | FERMT3 | 1 | 2 | 0 | 0 | T |
E7EUT5 | Glyceraldehyde-3-phosphate dehydrogenase | 109 | GAPDH | 0 | 3 | 0 | 0 | T |
A2AB27 | Guanine nucleotide-binding protein-like 1 | 49 | GNL1 | 4 | 4 | 0 | 2 | S |
P02724 | Glycophorin a | 133 | GYPA | 3 | 4 | 0 | 0 | T |
P02724, A0A087WU29 | Glycophorin a | 146 | GYPA | 3 | 4 | 0 | 2 | S |
P68871 | Hemoglobin subunit beta | 13 | HBB | 1 | 2 | 0 | 0 | T |
P69891 | Hemoglobin subunit gamma 1 | 53 | HBG1;HBG2 | 3 | 1 | 0 | 2 | S |
E9PHG0 | Kell blood group, metallo-endopeptidase | 28 | KEL | 3 | 5 | 0 | 3 | S |
Q8IY33 | Mical like 2 | 143 | MICALL2 | 5 | 6 | 3 | 1 | S |
Q00013 | Membrane palmitoylated protein 1 | 16 | MPP1 | 0 | 3 | 0 | 0 | T |
C9J6D1 | Nucleosome assembly protein 1 like 4 | 53 | NAP1L4 | 4 | 4 | 1 | 0 | S |
P00558 | Phosphoglycerate kinase 1 | 203 | PGK1 | 1 | 2 | 0 | 0 | S |
Q92508 | Piezo type mechanosensitive ion channel component 1 | 1820 | PIEZO1 | 2 | 3 | 0 | 0 | S |
F8WE65 | Peptidylprolyl isomerase a | 77 | PPIA | 2 | 1 | 0 | 0 | S |
P10644 | Protein kinase camp-dependent type i regulatory subunit alpha | 6 | PRKAR1A | 3 | 3 | 0 | 1 | T |
Q00577 | Purine rich element binding protein a | 183 | PURA | 1 | 2 | 0 | 0 | T |
Q9Y4G8 | Rap guanine nucleotide exchange factor 2 | 585 | RAPGEF2 | 1 | 2 | 0 | 0 | S |
P11166 | Solute carrier family 2 member 1 | 490 | SLC2A1 | 3 | 4 | 0 | 2 | S |
P02549 | Spectrin alpha, erythrocytic 1 | 421 | SPTA1 | 1 | 3 | 0 | 0 | S |
P02549 | Spectrin alpha, erythrocytic 1 | 2191 | SPTA1 | 1 | 2 | 0 | 0 | T |
P11277 | Spectrin beta, erythrocytic | 2128 | SPTB | 3 | 3 | 0 | 1 | S |
B8ZZJ0 | Small ubiquitin-like modifier 1 | 2 | SUMO1 | 4 | 6 | 0 | 3 | S |
E5RJ93 | Transcription elongation factor a1 | 57 | TCEA1 | 2 | 2 | 0 | 0 | S |
A0A087WZA9 | Transmembrane protein 120a | 167 | TMEM120A | 0 | 4 | 0 | 0 | S |
F8VZH8 | Unc-13 homolog a | 34 | UNC13A | 3 | 4 | 2 | 0 | T |
F8VZH8 | Unc-13 homolog a | 35 | UNC13A | 3 | 4 | 2 | 0 | T |
F8VZH8 | Unc-13 homolog a | 33 | UNC13A | 3 | 4 | 2 | 0 | S |
F5GWT4 | Wnk lysine deficient protein kinase 1 | 185 | WNK1 | 4 | 4 | 0 | 2 | S |
F5GWT4 | Wnk lysine deficient protein kinase 1 | 167 | WNK1 | 3 | 0 | 0 | 1 | S |
O43149 | Zinc finger zz-type and ef-hand domain containing 1 | 2444 | ZZEF1 | 3 | 3 | 0 | 2 | S |
