Fig. 1: The crAss-like phage assemblage.

a Phylogenetic tree of the TerL protein of crAss-like phages. CrAss-like groups are marked with red color. Previously analyzed crAss-like sequences are highlighted in yellow. Cultured phages are marked with bold font. Numbers in green circles indicate genomes for which the gene conservation pattern is shown in c. b Some key genome features of CrAss-like cMAGs. In parentheses are numbers on distinct genomes (sharing <90% of similarity at the DNA level). c Pattern of gene conservation in crAss-like phages. TerL terminase large subunit, portal portal protein, gene77 putative structural protein (gene 77), MCP major capsid protein, gene75 putative structural protein (gene 75), gene74 putative structural protein (gene 74), gene73 putative structural protein (gene 73), IHF_54 IHF subunit (gene 54), IHF_53 IHF subunit (gene 53), Ttub Tail tubular protein (P22 gp4-like), Tstab tail stabilization protein (P22 gp10-like), gene49 uncharacterized protein (gene 49), gene86 putative structural protein (gene 86), PDDEXK PD-(D/E)XK family nuclease, DnaB phage replicative helicase, DnaB family, primase DnaG family primase, SNF2 SNF2 helicase, SF1 SF1 helicase, ATP_43b AAA domain ATPase, PolB DNA polymerase family B, PolA DNA polymerase family A, Thy1 thymidylate synthase, dUTP dUTPase, UDG Uracil-DNA glycosylase, MPP metallophosphatase, Rep_Org replisome organizer protein, RNR ribonucleotide reductase, phage_O bacteriophage replication protein O (gene10 of IAS virus), gene48b phage endonuclease I, dNK deoxynucleotide monophosphate kinase.