Fig. 6: Spatial transcriptomic profiles of patient autopsies. | Nature Communications

Fig. 6: Spatial transcriptomic profiles of patient autopsies.

From: Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

Fig. 6: Spatial transcriptomic profiles of patient autopsies.

a Imaging from RNAscope showing fluorescence of target genes and imaging from GeoMx DSP defining regions of gene expression measurement for COVID Patient #4. b Close up of few selected regions of interest (ROI). c Cellular composition of 107 tissue regions. Each column shows the cell proportions within a single alveolar segment, as estimated from mixed cell deconvolution of GeoMx RNA data. Controls are from excess lung material from healthy lung transplant donors.

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