Fig. 4: Clinical parameters.

Weight (a), estimated Glomerular Filtration Rate (eGFR) (b), urinary protein secretion (c), troponin (d), and Left Ventricular Mass Index (LVMI) (e) was monitored during the course of the trial for all patients. eGFR was calculated using the Chronic Kidney Disease-Epidemiology Collaboration formula. Values from Magnetic Resonance Imaging (MRI) and Echocardiography (ECHO) are shown for LVMI (e). Patient 3 did not attend all cardiac assessments and has been omitted from Fig. 4e.