Table 1 Demographics and characteristics of patients enrolled in this study.

From: Targeting NSD2-mediated SRC-3 liquid–liquid phase separation sensitizes bortezomib treatment in multiple myeloma

Characteristics

Total (n = 133)

NDMM (n = 82)

RRMM (n = 51)

Median age (range)

63 (37–87)

59 (37–79)

66 (46–87)

Gender

    Male

78 (58.6%)

47 (57.3%)

33 (64.7%)

    Female

55 (41.4%)

35 (42.7%)

18 (35.3%)

Chromosomal abnormalities (%)a

    t (4;14)

22 (16.5%)

9 (10.9%)

13 (25.4)

    t (11;14)

19 (14.3%)

10 (12.2%)

9 (10.9%)

    t (14;16)

5 (3.75%)

3 (3.65%)

2 (3.92%)

    del13q,del17p

50 (37.6%)

32 (39%)

18 (35.3%)

R-ISS stage

    I

35 (26.3%)

26 (31.7%)

9 (17.6%)

    II

47 (35.3%)

27 (32.9%)

20 (39.2%)

    III

51 (38s.3%)

19 (23.2%)

32 (62.7%)

Induction or maintenance regimen

    VD

11 (8.3%)

11 (13.4%)

0 (0)

    VCD

93 (69.9%)

62 (75.6%)

31 (60.8%)

    VTD

29 (21.8%)

9 (11%)

20 (39.2%)

  1. NDMM newly diagnosed MM, rrMM refractory or relapsed MM, BD bortezomib, dexamethasone, BCD bortezomib, dexamethasone, cyclophosphamide, VTD bortezomib, thalidomide, dexamethasone
  2. aThe status of 1 patient is unknown