Fig. 2: Associations between inflammation-dependent cis-eQTLs and cell type enrichment. | Nature Communications

Fig. 2: Associations between inflammation-dependent cis-eQTLs and cell type enrichment.

From: Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease

Fig. 2: Associations between inflammation-dependent cis-eQTLs and cell type enrichment.

a One hundred and twenty-five out of 190 inflammation-dependent cis-eQTLs are associated with cell type enrichment. X-axis indicates gene IDs of cis-eQTLs. Y-axis indicates the number of associated enriched cell types (only n > 3 are shown). b Three examples. Left and middle panel, X-axis indicates cell type-enrichment scores derived from xCell. Y-axis indicates scaled expression levels of cis-eQTL genes. Colors indicate different genotypes. Right panel, X-axis indicates the genotype of cis-eQTL SNPs genotype, and Y-axis indicates scaled expression levels of cis-eQTL genes. Box plots show medians and the first and third quartiles (the 25th and 75th percentiles), respectively. The upper and lower whiskers extend the largest and smallest value no further than 1.5 × IQR (n = 280 samples). Source data are provided as a Source Data file).

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