Fig. 3: Fructose promotes a more inflammatory phenotype.
From: Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
Extracellular cytokine release of A IL-1β, B IL-6, C IL-8, D IL-10 and E TNF. F Heatmaps displaying the normalised read counts of selected cytokines from RNA-seq analysis of monocytes treated with glucose or fructose (both 11.1 mM) stimulated with LPS (10 ng/mL) for 24 h. G Representative immunoblot and pooled data of downstream mTOR target pS6 with housekeeping control, actin. Statistical significance was assessed using a one-sample t test (A–E) or an unpaired, two-tailed t test (G). Data are representative of five (A, B, D, E), four (C), three (F) and six independent experiments (G) and are expressed as mean ± SEM. Source data are provided as a Source Data file.
