Fig. 3: Scope of six-membered triorgano-substituted silicon-stereogenic heterocycles. | Nature Communications

Fig. 3: Scope of six-membered triorgano-substituted silicon-stereogenic heterocycles.

From: Enantioselective construction of six- and seven-membered triorgano-substituted silicon-stereogenic heterocycles

Fig. 3: Scope of six-membered triorgano-substituted silicon-stereogenic heterocycles.

Reaction conditions: 1 (0.1 mmol), [Rh(cod)Cl]2 (1 mol%), L1 (3 mol%) in toluene (1 mL) at 70 °C for 6 h. a Reaction was performed at 5 mmol scale. b L5 was used as ligand. c [Rh(cod)Cl]2 (4 mol%), L1 (8 mol%) was used. d [Rh(cod)Cl]2 (2 mol%), L1 (4 mol%) in toluene (1 mL) at 60 °C for 8 h. e [Rh(cod)Cl]2 (2 mol%), L1 (6 mol%) was used. f L7 was used as ligand. X-ray crystallographic analysis of 2j allowed to determine the absolute configuration; and configurations of the products 2 were assigned by analogy.

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