Fig. 5: Genotype and image feature association for an eQTL targeting lactate dehydrogenase D (LDHD) in colon samples. | Nature Communications

Fig. 5: Genotype and image feature association for an eQTL targeting lactate dehydrogenase D (LDHD) in colon samples.

From: Joint analysis of expression levels and histological images identifies genes associated with tissue morphology

Fig. 5: Genotype and image feature association for an eQTL targeting lactate dehydrogenase D (LDHD) in colon samples.The alternative text for this image may have been generated using AI.

a Boxplot of association between genotype rs8059637 (x-axis) and image feature 799 values for all samples (y-axis), the box hinges are the first quartile, the median, and third quartile of the image feature values, respectively, the lower whisker ranges from the bottom hinge to no less than 1.5*IQR (inter-quartile range), the upper whisker ranges from the top hinge to no more than 1.5*IQR; b same axes as (a), but points are the colon images with jitter added to separate the images; c relative abundance of LDHD expression across GTEx tissues, with colon—traverse showing substantial expression levels, boxplot defined the same as (a) with outlier points defined as greater than or less than the whisker range; d images in the top 10% of values for image feature 799; e images in the bottom 10% of values for image feature 799.

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