Table 1 Overview of analyzed AAV samples.

From: Adeno-associated virus capsid assembly is divergent and stochastic

Serotype

Name

Expression system

Stoichiometry by LC–UV/MS (VP1%:VP2%:VP3%)

Best scoring simulation (VP1%:VP2%:VP3%)

AAV1

AAV1 VP3-only

SF9

—

0:0:100

AAV1

AAV1

SF9

—

4:1:95

AAV8

AAV8_1

SF9

—

1:3:96

AAV8

AAV8_2

SF9

1:9:90

1:10:89

AAV5

AAV5

SF9

1:4:95

1:5:94

AAV9

AAV9

HEK293

6:16:78

6:14:80

  1. Overview of analyzed AAV serotypes with their origin, reference name used in this studies, and expression platform alongside the experimentally determined bulk VP ratios (if available). The best matching bulk VP ratio is based on simulation scorings shown in Fig. 5.
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