Fig. 4: OPA1 deletion inhibits the formation of IM/matrix MDVs. | Nature Communications

Fig. 4: OPA1 deletion inhibits the formation of IM/matrix MDVs.

From: Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs

Fig. 4

Quantification of MDVs positive for PDH (a), mtHSP70 (b), NDUFA9 (TOM20-negative) (c), as well as TOM20-positive (mtHSP70-negative) (d) in immunofluorescence images of WT (blue) and OPA1 KO (red) MEFs. Each data point represents one cell. Bars represent the average of 23 cells (except for PDH where n = 20) in three independent experiments ± SD. Two-sided t-test.

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