Fig. 3: The tgs operon is present in other staphylococcal species and functional. | Nature Communications

Fig. 3: The tgs operon is present in other staphylococcal species and functional.

From: Coagulase-negative staphylococci release a purine analog that inhibits Staphylococcus aureus virulence

Fig. 3: The tgs operon is present in other staphylococcal species and functional.

a Phylogenetic analysis of the 6-TG operon using completed and draft Staphylococcus genomes. Black triangles represent a clade that was collapsed because their internal bootstrap values were <50%. SCa S. capitis, SCh S. chromogenes, SE S. epidermidis, SP S. pseudintermedius. b Simultaneous antagonism assay of tgs-negative and -positive staphylococcal strains on TSA. c Simultaneous antagonism assay using RN4220 pEmpty and pVCU116 tgs on TSA. d S. aureus was cultured in TSB containing supernatant from RN4220 pEmpty or pVCU116 tgs and plated 24 h.p.i and CFU/mL were enumerated. Results are pooled from two independent experiments, each with n = 3 replicates per condition. Data are shown as mean ± SD (**p ≤ 0.01. Two-sided unpaired t-test).

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