Fig. 4: Differentiation depends on continuous exposure to white matter.
From: The white matter is a pro-differentiative niche for glioblastoma
a schematic representation of experimental workflow. b Kaplan Meier survival plot of nude mice injected with G144 cells acutely isolated from the bulk, corpus callosum (CC) and striatum of primary xenografts. n = 6 mice/group. c Representative images of secondary GFP+ tumours stained for neurofilament (grey) to identify axonal bundles, SOX10 (red) and DAPI (blue). Tumour areas from the indicated brain regions are shown revealing a differentiation pattern identical to primary lesions. Scale = 50 µm.
