Fig. 5: dNAM origami and message recovery rates in the presence of increasing errors. | Nature Communications

Fig. 5: dNAM origami and message recovery rates in the presence of increasing errors.

From: An alternative approach to nucleic acid memory

Fig. 5

Simulations were performed to determine the theoretical success rates for correctly decoding individual dNAM origami and recovering encoded messages. In (a), the mean number of dNAM origami needed to successfully recover messages of increasing length with (circles) or without (squares) redundant bits are plotted. In (b), the mean success for recovering both individual origami (triangles) and the entire message (diamonds) are plotted against the mean number of errors per origami (errors were randomly generated for simulated data). Simulation recovery rates are averages of all message sizes tested (160 to 12,800 bits). For comparison, the mean success rate for experimental data is also plotted (open circles). For experimental data, the mean success was estimated by comparing the decode algorithm’s results with that of the template-matching algorithm. All simulations were repeated 40 times. Experimental data were derived from 3 independent DNA-PAINT recordings.

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