Fig. 5: Effect of V2C MXenzyme on intracellular ROS scavenging and cytoprotection.
From: 2D vanadium carbide MXenzyme to alleviate ROS-mediated inflammatory and neurodegenerative diseases
V2C MXenzyme protects L929 cells from oxidative stress as induced by a UV irradiation (n = 6 for each group in cell viability and n = 4 for each group in ROS intensity), c, d H2O2 (n = 5 for each group in (c), n = 6 for each group in (d) cell viability and n = 5 for each group in (d) ROS intensity), and g Fenton reagent (FeSO4 + H2O2, n = 4 for each group) via ROS scavenging. V2C MXenzyme protects PC12 cells from oxidative stress as induced by b UV irradiation (n = 6 for each cell viability group and n = 4 for each ROS intensity group), e, f H2O2 (n = 6 for each group in (e), n = 6 for each group in (d) cell viability and n = 4 for each group in (d) ROS intensity), and h Fenton reagent (n = 4 for each group) via ROS scavenging. The central line represents the median (50th percentile), box limits represent the 25th and 75th percentiles and whiskers represent 1.5× the extent of the interquartile range. The cellular i GSH and j GSSG levels in both L929 cells and PC12 cells after different treatments (n = 3 for each group). Data presented as mean ± SD, and asterisks indicated significant difference (*p < 0.05, **p < 0.01, and ***p < 0.001) as compared with the control group using one-way analysis of variance (ANOVA).
