Fig. 4: Exploring different nanoenvironments of chromatin modifications in single cells. | Nature Communications

Fig. 4: Exploring different nanoenvironments of chromatin modifications in single cells.

From: Cellular macromolecules-tethered DNA walking indexing to explore nanoenvironments of chromatin modifications

Fig. 4

a Selected merged cell images for five histone PTMs. The red, green, and blue fluorescence spots each indicated the combination sites of 5hmU/PTM, 5fU/PTM, and 5hmC/PTM. The scale bar is 5 μm. b The spot percentages of three combination sites of single cells in five samples (cell numbers = 52, 34, 32, 43, and 38, respectively). c Analysis of the overlap or cluster of different spots. For the experiments of cell imaging in all figures, five times were repeated independently with similar results.

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