Fig. 4: Therapeutic antitumor efficacy in an MC38 tumor model. | Nature Communications

Fig. 4: Therapeutic antitumor efficacy in an MC38 tumor model.

From: Intratumoral immunotherapy using platelet-cloaked nanoparticles enhances antitumor immunity in solid tumors

Fig. 4

a Schematic timeline of the efficacy study. Tumors were treated with a sucrose control (n = 7), free R848 (n = 7), PEG-NP-R848 (n = 7), and PNP-R848 (n = 8). b Average tumor growth kinetics after treatment (mean ± SEM). c Individual tumor growth kinetics after treatment (N = naive challenge, RC = re-challenge). The insets depict the growth kinetics after each re-challenge. d Progression-free survival (tumor size < 200 mm3) of mice after treatment. e Body weight of mice after treatment (mean + SD). Source data are provided as a Source Data file.

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