Table 1 Comparison of kinetic and thermodynamic parameters describing T3SA+ virion-β1 integrin interaction in the presence of either Mn2+ or Mg2+.
From: Reovirus directly engages integrin to recruit clathrin for entry into host cells
T3SA+ | Mn2+ | Mg2+ |
|---|---|---|
BF [%] | 19 ± 7 | 8 ± 3 |
koff [s-1] | 0.4 ± 0.2 | 2.1 ± 0.4 |
kon [µM-1 s-1] | 5.83 ± 0.6 | 3.83 ± 0.08 |
KD [nM] | 68 ± 56 | 548 ± 125 |
xu [nm] | 0.69 ± 0.07 | 0.65 ± 0.03 |