Table 2 Comparison of kinetic and thermodynamic parameters describing sialic acid dependence of reovirus virion interaction with β1 integrin.

From: Reovirus directly engages integrin to recruit clathrin for entry into host cells

Mn2+

T3SA+

T3SA-

T3SA+ +Neu5Ac

BF [%]

19 ± 7

7 ± 1

6 ± 2

koff [s-1]

0.4 ± 0.2

0.58 ± 0.2

0.57 ± 0.1

kon [µM-1 s-1]

5.83 ± 0.6

5.62 ± 0.3

4.92 ± 1.1

KD [nM]

68 ± 56

103 ± 44

116 ± 45

xu [nm]

0.69 ± 0.07

0.50 ± 0.04

0.41 ± 0.02

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